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tag hiv pathogenesis genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Top 7 in Genomics & Genetics
Sabrina Richards | Sep 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics and related areas, from Faculty of 1000
Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
Microscope image of A549-ACE2 lung cells coinfected with SARS-CoV-2 and a reporter vector containing a key regulatory variant of interest in the region on human chromosome 3
How Genes from Neanderthals Predispose People to Severe COVID-19
Alakananda Dasgupta | Feb 22, 2023 | 4 min read
Researchers dissect the Neanderthal-derived region on chromosome 3 that drives severe COVID-19 to zero in on the key causal variants.
HIV’s Stealth Revealed
Ed Yong | Nov 21, 2013 | 3 min read
HIV-1 evades the immune system with a protein shield, which can be lifted.
The Scientist Staff | Mar 28, 2024
Research Notes
Kate Devine | Oct 1, 2000 | 5 min read
HIV Hitches a Ride The statistics are grim: More than 34 million people worldwide affected with HIV/AIDS, and 800,000- 900,000 cases in the United States with a steady rate of 40,000 new HIV infections each year. Fueled by such statistics, HIV research continues with scientists at the National Institute of Allergy and Infectious Diseases (NIAID) recently discovering a mechanism providing insight into the pathogenesis of the virus in which HIV may hitch a ride from select cells to target cells.
How HIV Destroys Immune Cells
Dan Cossins | Dec 19, 2013 | 4 min read
During HIV infection, CD4 T cells in lymphoid tissues initiate a highly inflammatory form of cell death that helps cripple the immune system.
 
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Annual NIH `Show And Tell' Celebrates Intramural Research Advances
Neeraja Sankaran | Sep 4, 1994 | 4 min read
Symposia: Monday, September 19, 8:45 a.m.-noon: NICHD Distinguished Alumni Symposium: Contributions of Basic Science to Human Biomedical Research (Bldg. 10, Masur Auditorium) Tuesday, September 20, 8:30 a.m.-noon: HIV Pathogenesis and Therapy (Bldg. 10, Masur Auditorium) Tuesday, 8:30 a.m.-noon: Apoptosis and the Cell Cycle (Bldg. 10, Lipsett Amphitheater) Wednesday, September 21, 8:30 a.m.-noon: Genetic Predisposition to Diseas

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