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tag broadly cross neutralizing antibodies evolution microbiology

False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021 | 10+ min read
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
The Role of Mom’s Microbes During Pregnancy
Carolyn A. Thomson and Kathy D. McCoy | Aug 1, 2021 | 10+ min read
Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.
HIV Evolves Vulnerability
Sabrina Richards | Oct 21, 2012 | 3 min read
In mutating to evade immune detection, HIV becomes susceptible to detection by different antibodies, suggesting new strategies for vaccination.
Woman in face shield and blue gown taking cotton swab of patient's mouth while patient sits inside of car
What You Should Know About New Omicron Subvariants
Natalia Mesa, PhD | May 17, 2022 | 6 min read
The presence and spread of new, more-infectious and immune-evading variants show that the coronavirus is not done mutating.
Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
Top 7 in Immunology
Edyta Zielinska | Aug 2, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000
Week in Review: June 15–19
Tracy Vence | Jun 19, 2015 | 3 min read
Eye on MERS; HIV vaccine design; evolution of Ebola; CRISPR meets optogenetics
The Last Vaccine Frontier
Brad Spellberg | Jun 1, 2011 | 10+ min read
Successful vaccines have been created to protect against pathogenic bacteria and viruses. Why aren’t there any for combating fungal infections?

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