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tag broadly cross neutralizing antibodies genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Envelope clue to general HIV vaccine
Tudor Toma | Aug 22, 2002 | 1 min read
HIV envelope glycoprotein complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques.
Neutralizing HIV
Kerry Grens | Jun 18, 2015 | 4 min read
Engineered immunogens based on conserved patches of the virus’s envelope protein point to new strategies for vaccine design.
Introduction to AAV Gene Therapies
Introduction to AAV Gene Therapies
Nicole Stivers, PhD | Jun 29, 2023 | 4 min read
Small-scale successes in rare disease treatments prime large-scale industry innovations.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Week in Review: January 23–27
Tracy Vence | Jan 29, 2017 | 3 min read
Chimeric embryos, organs; restrictions on marijuana research; toward temperature-independent vaccine storage; broadly neutralizing antibodies show promise for HIV treatment, prevention; Trump’s first week in office affects scientists; final three WHO Director-General candidates selected
Genomes Gone Wild
Megan Scudellari | Jan 1, 2014 | 10+ min read
Weird and wonderful, plant DNA is challenging preconceptions about the evolution of life, including our own species.
Human DNA abstract dotwork vector illustration made of cloud of colored dots.
Adapting with a Little Help from Jumping Genes
Christie Wilcox, PhD | Jan 17, 2022 | 10+ min read
Long lambasted as junk DNA or genomic parasites, transposable elements turn out to be contributors to adaptation.
"Big Cross" Lands Sticklebacks in the Spotlight
David Secko | Nov 7, 2004 | 5 min read
Marine threespine sticklebacks haven't morphologically changed in an estimated 10 million years, but their freshwater offshoots show no signs of slowing down. These 5-cm-long, freshwater fish have undergone a recent evolutionary change, variably losing their calcified body armor and retractable pelvic and dorsal spines. Remarkably, isolated marine and freshwater sticklebacks can be hybridized in the laboratory, a fact that is allowing researchers to analyze the genetics behind their natural dive

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