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tag chronic hiv infection cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Illustration of HIV virus
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD | Dec 12, 2022 | 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Molecular Biology
The Scientist Staff | Jul 5, 1992 | 1 min read
N. Kato, M. Hijikata, Y. Ootsuyama, M. Nakagawa, et al., "Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis," Proceedings of the National Academy of Sciences, 87:9524-28, 1990. Nobuyuki Kato (National Cancer Center Research Institute, Tokyo): "Hepatitis C virus (HCV) is the major etiological agent of posttransfusional non-A, non-B hepatitis (NANBH) throughout the world. NANBH frequently develops into chronic hepatitis and cirrhosis and
The Infection-Chronic Disease Link Strengthens
Ricki Lewis | Sep 3, 2000 | 6 min read
Infection" is usually associated with an oozing sore, a bout with the flu, or an outbreak in some exotic place. But infectious organisms lie behind many chronic illnesses too, and an increasingly molecular approach to diagnosis is clarifying some of these relationships. An invited panel discussed "The Infectious Etiology of Chronic Diseases" at the second International Conference on Emerging Infectious Diseases, held in Atlanta July 16-19. Chronic diseases take a huge toll. "In the [United St
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Glowing red DNA on bluish background
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD, Technology Networks | Jun 21, 2023 | 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
How HIV Destroys Immune Cells
Dan Cossins | Dec 19, 2013 | 4 min read
During HIV infection, CD4 T cells in lymphoid tissues initiate a highly inflammatory form of cell death that helps cripple the immune system.
 
Unique Antibodies Open Path Toward New HIV Vaccines
Amanda B. Keener | Jan 27, 2017 | 3 min read
A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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