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tag polyunsaturated fatty acids cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Philip Leder, Who Deciphered Amino Acid Sequences, Dies
Ashley Yeager | Feb 12, 2020 | 4 min read
The Harvard Medical School researcher’s work on the genetic basis of protein coding and production led him to make groundbreaking discoveries in immunology, molecular biology, and cancer genetics.
Cell Biology
Stephen Hoffert | Oct 26, 1997 | 3 min read
Edited by: Stephen P. Hoffert S.A. Kliewer, J.M. Lenhard, T.M. Willson, I. Patel, D.C. Morris, J.M. Lehmann, "A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation," Cell, 83:813-9, 1995. (Cited in more than 100 papers through September 1997) Comments by Jüergen M. Lehmann, Glaxo Wellcome Inc. Research and Development, Research Triangle Park, N.C. More than 15 million people in the United States suffer from non-insulin d
In Failing Hearts, Cardiomyocytes Alter Metabolism
Amanda B. Keener | Jun 1, 2016 | 2 min read
While the heart cells normally burn fatty acids, when things go wrong ketones become the preferred fuel source.
Reductio Ad Amino Acid
Bob Sinclair | Feb 1, 1999 | 10+ min read
Date: February 1, 1999Fusion/Tag Proteases TableProteolytic Enzymes TableTable 3Table 4 A proteome analysis aims to characterize all proteins expressed by an organism or tissue. The next step will be to correlate a protein profile with the appropriate genome, and beyond that researchers will want to understand the correlations between levels of proteins, co- and post-translational modifications, and cell or tissue activity. Many of the technologies that are necessary to realize this goal are de
Light blue dots forming keys over a navy background with small red dots.
A Double Lock Gates Calcium Signaling
Danielle Gerhard, PhD | Nov 13, 2023 | 6 min read
Recent studies settle a debate over how the second messenger NAADP, with no known binding site, evokes calcium release from ion channels. 
Tag, You're It
Carina Storrs | Feb 1, 2014 | 7 min read
A guide to DNA-encoded libraries for drug discovery

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