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Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
THE STATE OF LIFE SCIENCE
Dennis Meredith | Apr 1, 2007 | 8 min read
By Dennis MeredithTHE STATE OF LIFE SCIENCENorth Carolina combines academic, industrial, government, and private resources to drive research, development, and manufacturing A half century ago, the world was only beginning to grasp the stunning implications of Watson's and Crick's double-helix DNA structure. Amidst those earliest glimmerings of the genetic revolution, North Carolina was already laying the foundation for its 21st-century success in biotechnology. In 1959, however, the evidence o
Mutants, And Their Suppliers, Are Key To Modern Research
Ricki Lewis | Sep 29, 1991 | 8 min read
Through History Mutants forged the field of genetics, starting with Gregor Mendel's short or tall, yellow or green, round or wrinkled pea plants. Since Mendel's work in the 19th century, geneticists have used white-eyed flies to demonstrate sex linkage and bread mold spore variants to study the recombination of traits that occurs during sexual reproduction. Christiane Nusslein-Volhard and Edward Lewis, two of this year's Lasker award winners, are being recognized for pioneering work in developm
Researchers Receiving MacArthur Fellowships Demonstrate 'Capacity To Make A Difference'
Bruce Anderson | Sep 14, 1997 | 6 min read
PRIZE WITH A PRICE: Science historian Peter Galison has taken some ribbing from his family since being named a MacArthur fellow. One could almost pity Peter Galison. A historian of science at Harvard University, Galison is one of seven members of the scientific community among the 23 recipients of this year's John D. and Catherine T. MacArthur Foundation Fellowships. The coveted five-year awards provide unrestricted support plus health insurance to talented individuals, with no reports or proj
Getting in Tune With the Enemy--Microbes
Joshua Lederberg | Jun 1, 2003 | 6 min read
Ned Shaw After a lapse of some decades, germs and disease have again been very much on our minds, largely because of the dreadful effect of AIDS throughout the world. We also have had a reawakened consciousness that globally prevalent diseases like tuberculosis and malaria remain historical scourges. Now the daily news tells us of new outbreaks such as severe acute pulmonary syndrome, or SARS, spreading from China, with an outcome that cannot be confidently predicted at this time. Throughout
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Blotting Technology's Permanence Is Assured As Its Applications In The Laboratory Flourish
Holly Ahern | Nov 27, 1994 | 10 min read
Advanced Biotechnologies Inc. Columbia, MD Advanced Genetic Technologies Corp San Diego, CA Ahlstrom Filtration Inc. Mount Holly Springs, PA American Bioanalytical Inc. Natick, MA Boehringer Mannheim Corp. Indianapolis, IN P.J. Cobert Associates St. Louis, MO Crescent Chemical Inc. Hauppauge, NY DuPont NEN Boston, MA Fluka Chemical Corp. Ronkonkoma, NY Gallard-Schlesinger Industries Inc. Carle Place, NY Hoefer Scientific

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