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tag antibiotic resistance genetics genomics culture

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | Jan 24, 2024 | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
The Evolution of Drug Resistance
Ruth Williams | Dec 18, 2011 | 3 min read
Researchers use whole-genome sequencing to keep tabs on the development of antibiotic resistance in bacteria.
Resistant to Failure
Cristina Luiggi | Feb 28, 2011 | 3 min read
A Duke University researcher survives a sticky situation at a federal research institution to make major strides in determining the genetic roots of Staphylococcus aureus antibiotic resistance.
How a Microbe Resists Its Own Antibiotics
Jef Akst | Feb 20, 2014 | 3 min read
Researchers reveal the molecular mechanisms of Streptomyces platensis’s defense from its own antibiotics, which inhibit fatty acid synthesis in other microbes.
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Overcoming Resistance
The Scientist | Apr 1, 2014 | 10+ min read
In the face of bacterial threats that can evade modern medicines, researchers are trying every trick in the book to develop new, effective antibiotics.
Infographic showing how a viral protein expression method links proteins and their coding instructions
Infographic: Phage Display Allows Rapid Screening of Millions of Peptides
Shelby Bradford, PhD | Dec 4, 2023 | 3 min read
A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.
A Y-shaped pink, blue, and light green antibody is in focus on a background of blurred pink and purple color, with other antibodies out of focus in the background.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.

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