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image: Targeting Tregs Halts Cancer’s Immune Helpers

Targeting Tregs Halts Cancer’s Immune Helpers

By | April 1, 2017

New monoclonal antibodies kill both cancer-promoting immunosuppressive cells and tumor cells in culture.

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image: Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

Anti-Flavivirus Antibodies Enhance Zika Infection in Mice

By | March 30, 2017

Researchers report evidence of antibody-dependent enhancement in a Zika-infected, immunocompromised mouse model.

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image: Experimental MERS Treatments Target Host Cell Receptor

Experimental MERS Treatments Target Host Cell Receptor

By | March 30, 2017

Researchers are searching for ways to prevent the coronavirus from attaching to DPP-4 receptors, blocking it from invading and replicating within host cells.

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image: Tetracycline Inventor Dies

Tetracycline Inventor Dies

By | March 15, 2017

Lloyd Conover, a longtime chemist at Pfizer, pioneered the concept of chemically altering natural antibiotics to create new drugs.

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image: WHO Lists Antibiotic Development Priorities

WHO Lists Antibiotic Development Priorities

By | February 27, 2017

The World Health Organization outlines critical-, high-, and medium-priority antibiotic development initiatives, calling on the public and private sectors to invest in additional R&D.

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image: Contributors

Contributors

By | February 1, 2017

Meet some of the people featured in the February 2017 issue of The Scientist.

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image: Discovering Novel Antibiotics

Discovering Novel Antibiotics

By | February 1, 2017

Three methods identify and activate silent bacterial gene clusters to uncover new drugs

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image: Unique Antibodies Open Path Toward New HIV Vaccines

Unique Antibodies Open Path Toward New HIV Vaccines

By | January 27, 2017

A family of broadly neutralizing antibodies from a chronically infected donor provides a schematic for designing vaccines and treatments that target multiple strains of the virus.

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image: Mouse Immunology Paper Retracted

Mouse Immunology Paper Retracted

By | December 16, 2016

A finding of misconduct spurs the retraction of a Science paper claiming to have identified a protein in mice that boosted immunity to both viruses and cancer.

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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