Contrary to previous assumptions that macrolide antibiotics completely block the exit tunnel of ribosomes, new evidence shows that some peptides are allowed to pass.
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Systems biologist Lone Gram describes her approach to combing the oceans for novel compounds that may be useful in the fight against pathogens.
Contributors
| March 1, 2013
Meet some of the people featured in the March 2013 issue of The Scientist.
A normally land-based microbiologist sets sail to find the building blocks of novel antibiotics in marine bacteria.
During development, communication between organs determines their relative final size.
Collective cell migration relies on a directional signal that comes from the moving cluster, rather than from external cues.
Watch the cell transplant experiments in zebrafish that suggest certain embryonic cells rely on intrinsic directional cues for collective migration.
Fecal transplants outcompeted traditional antibiotics at curing a deadly intestinal infection.
Despite decades of work, compounds in frog skins have failed to yield new antibiotics. Why?
The science images and videos that captured our attention in 2012
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