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tag lipoprotein lipase deficiency cell molecular biology developmental biology

Let It Shine
Jorge Cortese | Mar 19, 2000 | 9 min read
Fluorescence Detection Products Courtesy of BD PharMingenMulticolor immunofluorescent cell staining showing cell surface FITC (green) staining and intracellular PE (orange) and APC (red) staining. Is radioactive detection of biomolecules destined to the same fate as the Berlin Wall? The multitude of nonisotopic detection methods now available suggests that the 21st century may come to be billed as the "nonisotopic research century." The broadest common denominator of this up and coming cast of
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
Notable
Jeffrey Perkel | Jun 9, 2002 | 3 min read
Z. Mourelatos et al., "miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs," Genes & Development, 16[6]:720-8, March 15, 2002. "A novel ribonucleoprotein (RNP) complex in HeLa cells was identified that contains two proteins implicated in spinal muscular atrophy (SMA), eIF2C2 (a member of the Argonaute family), and numerous small RNAs ~22 nucleotides in length. The finding that microRNAs (miRNAs) associate with eIF2C2 ties together genetic findings demonstrating that Argona
Preimplantation Genetic Diagnosis: The Next Big Thing?
Ricki Lewis | Nov 12, 2000 | 9 min read
Courtesy of David Hill, ART Reproductive Center Inc.Two separated blastomeres subjected to FISH analysis to check the chromosomes. In early October, preimplantation genetic diagnosis (PGD) made headlines when a Colorado couple used assisted reproductive technology (ART) to have a baby named Adam, whose umbilical cord stem cells could cure his six-year-old sister Molly's Fanconi anemia.1 When Adam Nash was a ball of blastomere cells, researchers at the Reproductive Genetics Institute at Illinois
Gene Therapy: Clinical Gains Yield A Wealth Of Research Opportunities
Franklin Hoke | Oct 3, 1993 | 8 min read
investigation that will carry advances forward The transfer of genetic materials into humans to correct diseases--gene therapy--is a new medical enterprise, barely three years old in the clinic. But in the short time since a research team at the National Institutes of Health in Bethesda, Md., first treated a young girl's genetically compromised immune system with a transfusion of her own DNA-corrected white blood cells on Sept. 14, 1990, gene therapy has grown to command considerable public
Mafia Wars
Jef Akst | May 31, 2010 | 10+ min read
An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.
Antibodies Making Their Way From The Clinic To The Research Lab
Holly Ahern | Sep 17, 1995 | 10 min read
if (n == null) The Scientist - The Immune Response The Scientist 9[18]:18, Sep. 18, 1995 Tools The Immune Response By Holly Ahern Imagine that you've just cloned a gene for a bacterial enzyme with unique structural properties and you want to find out more about it. What natural role does the enzyme play, you wonder, and do organisms other than bacteria produce it? To answer these questions, you could screen countless genomic libraries for clones bearing si

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