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tag lipoprotein lipase deficiency genetics genomics neuroscience

The Genes of Parkinsonā€™s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
Eat Your Way to Better DNA
Kate Travis | Sep 1, 2006 | 10+ min read
FEATURE Eat Your Way to Better DNA RICK CONTRERAS Why what your grandmother ate while pregnant with your mother might affect your children's health, and other findings from the growing field of nutrigenomics. By KATE TRAVIS Jose M. Ordovas has been studying the role of lipoproteins in heart disease for decades. His laboratory and others have tried to tease out how these proteins factor into why some people can eat an unheal
Scientists Strike a Cord
Rabiya Tuma | Feb 9, 2003 | 6 min read
Courtesy of SR Eng  BABY STAINS: The head of a transgenic murine embryo in which a marker enzyme has been specifically expressed in the sensory neurons of the trigeminal and dorsal root ganglia. The marker allows staining of the projections of these neurons into, among other areas, the hindbrain and spinal cord. (S.R. Eng et al., "Defects in sensory axon growth precede neuronal death in Brn3a-deficient mice," J Neurosci, 21:541-9, 2001.) Somewhere in the 200 million bases of the human ge
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
The Genes of Parkinsons Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 7 min read
By Bobby Thomas and M. Flint Beal The Genes of Parkinson’s Disease The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure. Gerald Slota It took centuries for the slumped posture, trembling hands, poor balance, and cognitive impairments that characterize Parkinson’s disease (PD) to be recognized as manifest
How Orphan Drugs Became a Highly Profitable Industry
Diana Kwon | May 1, 2018 | 10+ min read
Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.
How Well Do Mice Model Humans?
Ricki Lewis | Oct 25, 1998 | 8 min read
STRIKING RESEMBLANCE: James Croom, who studies Down syndrome mice at North Carolina State University, says the animals are providing valuable information useful to humans. When a page-one article in the May 3, 1998, Sunday New York Times portrayed angiogenesis inhibitors that fight cancer in mice as being possible just around the corner for humans, criticism for raising false hopes erupted. Merely 10 weeks later, however, when researchers from the University of Hawaii reported cloning the fi

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