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tag adeno associated virus developmental biology neuroscience immunology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018 | 4 min read
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Creative Expression: Mammalian Expression Vectors and Systems
Christopher Smith | Feb 1, 1998 | 7 min read
Date: February 2, 1998 Chart 1 Chart 2 Prokaryotic expression systems, reviewed in the September 1, 1997, issue of The Scientist were part of the early repertoire of research tools in molecular biology. Although the expression of recombinant protein in prokaryotes provided a means to develop other research tools (antibodies, for example ) and study basic aspects of biological function, the scope and depth of this research were limited, especially with regard to eukaryotic proteins. The de novo
Distinguishing Th1 and Th2 Cells
Jeffrey Perkel | May 13, 2001 | 10+ min read
Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr
Articles Alert
Simon Silver | Jun 24, 1990 | 7 min read
The Scientist has asked a group of experts to comment periodically upon recent articles that they have found noteworthy. Their selections, presented herein every issue, are neither endorsements of content nor the result of systematic searching. Rather, the list represents personal choices of articles the columnists believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article, 3501 Market St., Philadelphia,
Turmoil Besets Wistar In Wake Of Koprowski's Ouster
Jean Wallace | Mar 1, 1992 | 10+ min read
The Wistar Institute in Philadelphia marks its 100th anniversary this year, but the mood at the nation's oldest independent biomedical research facility is hardly jubilant. The institute has been in turmoil for the last year, after the abrupt ouster of longtime director Hilary Koprowski, the famed virologist and immunologist who transformed Wistar from a dilapidated museum into a world-renowned research center. The commotion recently was stirred up further, when the 75-year-old Koprowski file
Radioimmunoassay: A Proven Performer In the Bio Lab
Rebecca Krumm | May 15, 1994 | 9 min read
AUTHOR: REBECCA KRUMM, pp.17 Date: May 16,1994 SUPPLIERS OF RADIOIMMUNOASSAY KITS, REAGENTS, AND SUPPLIES The following companies offer radioimmunoassay supplies and equipment. Please contact the companies directly for more information concerning specific products. Advanced Chemtech 5609 Fern Valley Rd. Louisville, Ky. 40228 (502) 969-0000 Fax: (502) 968-1000 AMAC Inc. 160B Larrabee Rd. Westbrook, Maine 04092 (207) 854-0426 Fax

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