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tag brca2 microbiology evolution

bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.
The Scientist’s 2019 Gift Guide
Emily Makowski | Dec 13, 2019 | 2 min read
Wishing you a sciency season’s greetings!
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 
Sweet science
Megan Scudellari | Sep 15, 2010 | 4 min read
Ever had the urge to take a nice crunchy bite of Drosophila or lick icing off a brain? You will after a visit to linkurl:Not So Humble Pie,;http://notsohumblepie.blogspot.com/ a blog run by scientist-turned-baker, Ms. Humble. A blogger who refers to herself as "a typical nerdy biological anthropologist turned stay at home mom," Ms. Humble -- who chooses to remain anonymous -- began the blog in October 2009. Since then, the popular blog has regularly featured science-themed baked goods, from zebr
One Link Found, Many to Go; The Rat's Now in the Ring; Red River for a Red Planet
Josh Roberts | May 18, 2003 | 4 min read
One Link Found, Many To Go Researchers at the UK's Cambridge Institute of Medical Research (CIMR) and Merck & Co. reported a link between cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and autoimmunity (H. Ueda et al., "Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease," Nature, e-pub ahead of print, doi:10.1038/nature01621, April 30, 2003). The researchers used positional cloning to search a 330 kb region surrounding the CTLA4 gene for polymorp
Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
A Push and a Pull for PARP-1 in Aging
Jack Lucentini(jlucentini@the-scientist.com) | Aug 1, 2005 | 6 min read
Understanding the mechanisms that underlie aging remains a bedeviling problem, but not because of a lack of answers.
MMTV and Breast Cancer
Douglas Steinberg | Apr 16, 2000 | 7 min read
Virus-Disease Links Are Hard to Forge Researchers confront skepticism, conflicting results, limited funding By Douglas Steinberg If genomics is glitzy nowadays, virus research is, well, gritty. Its latest heyday, when HIV was shown to cause AIDS, only masked its true nature. Associating viruses with diseases has always been particularly difficult and labor intensive. Cause-and-effect relationships are maddeningly elusive.1 Consider the following two questions: Does infection by mouse mammary

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