Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.

The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.

A novel PET tracer targeting a receptor in myeloid cells can help monitor disease progression in a mouse model of multiple sclerosis.

Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.

Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.

S. Ghosh, D. Baltimore, "Activation in vitro of NF-kB by phosphorylation of its inhibitor IkB," Nature, 344:678-82, 1990. Sankar Ghosh (Whitehead Institute for Biomedical Research, Cambridge, Mass.): "This paper brings together two areas of rapidly moving research: the role of protein phosphorylation and control of transcriptional regulation. The inhibitor IkB not only keeps the transcription factor NF-kB in the cytoplasm--away from DNA--but also directly prevents it from binding to DNA. By sh

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.