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tag patent evolution

Week in Review: August 18–22
Tracy Vence | Aug 22, 2014 | 3 min read
Neanderthal extinction; eradicating polio; virus takes down massive algal bloom; receptor behind the hummingbird’s sweet tooth; legal threat for PubPeer; price tag of scientific fraud
Week in Review: June 16–20
Tracy Vence | Jun 20, 2014 | 2 min read
Early Neanderthal evolution; developing antivirals to combat polio; the mouth and skin microbiomes; insect-inspired, flight-stabilizing sensors
Genome Investigator Craig Venter Reflects On Turbulent Past And Future Ambitions
Karen Young Kreeger | Jul 23, 1995 | 8 min read
And Future Ambitions Editor's Note: For the past four years, former National Institutes of Health researcher J. Craig Venter has been a major figure in the turbulent debates and scientific discoveries surrounding the study of genes and genomes. Events heated up in 1991, when NIH attempted to patent gene fragments, which were isolated using Venter's expressed sequence tag (EST)/complementary DNA (cDNA) approach for discovering human genes (M.A. Adams et al., Science, 252:1651-6, 1991). NIH's mo
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Credit for CRISPR: A Conversation with George Church
Bob Grant | Dec 29, 2015 | 5 min read
The media frenzy over the gene-editing technique highlights shortcomings in how journalists and award committees portray contributions to scientific discoveries.
Aptamers Identify Protein Signatures
Ricki Lewis | Apr 1, 2001 | 3 min read
Graphic: Leza BerardoneA technique not deemed "sexy" enough for commercialization a decade ago may finally find its niche in proteomics. SomaLogic Inc. of Boulder, Colo. is pioneering aptamers, which are modified DNA molecules that bind specific proteins in body fluid samples. Aptamers are initially selected for specific binding activities from a huge starting pool, then variants are obtained during subsequent rounds of amplification. The technology builds on the ability of aptamers to bind tena
Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
Drug Makers on the Apoptotic Trail
Ted Agres | Jun 24, 2001 | 4 min read
Apoptosis, a key process in the development of embryonic tissue differentiation, later helps to regulate the normal cellular life cycle by destroying damaged cells. When something goes awry, too little apoptosis can make cancer cells resistant to chemotherapy and even death-defiant. At the other extreme, premature or excessive apoptosis has been linked to neurodegenerative diseases, such as Alzheimer's, and to nerve cell loss in strokes. Not surprisingly, many major pharmaceutical companies rec
Combinatorial Libraries: Life's Tinker Toys
Gail Dutton | May 18, 2003 | 9 min read
Courtesy of UC Davis Medical Center  COMBI-KING: Kit Lam brings his expertise in combinatorial chemistry, an innovative technique for creating millions of new chemical compounds in just days, to the UC Davis Cancer Center. It's the new mix and match. In the computer industry, programmers refer to modularity--the ability to shuffle different sections of computer code to create new software. In the life sciences, the modules are peptides or molecular fragments that can be combined to yield
60 Members Elected to NAS
Barry Palevitz | Jun 25, 2000 | 6 min read
Editor's Note: On May 2, the National Academy of Sciences announced the election of 60 new members and 15 foreign associates from nine countries in recognition of their distinguished and continuing achievements in original research. Nearly half of the new members are life scientists. In this article, The Scientist presents photographs of some of the new members and comments from a few of them on their careers and on past and current research. A full directory of NAS members can be found online a

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