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tag chromosome folding domains immunology developmental biology

One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.
COVID-19 Infections May Reshape Genetic Landscape
Holly Barker, PhD | Mar 30, 2023 | 3 min read
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests. 
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Microscopy image of the cnidarian <em>Hydractinia symbiolongicarpus&nbsp;</em>with cell nuclei stained blue and oocytes stained yellow
Ancient Immunoglobulin Genes Help Cnidarians Decide to Fight or Fuse
Sophie Fessl, PhD | Oct 11, 2022 | 4 min read
Immunoglobulin genes might have evolved much earlier than previously expected, perhaps even in the common ancestor of Cnidarians and Bilateria, a study suggests.
obituary, obituaries, roundup, end of the year, COVID-19, SARS-CoV-2, pandemic, coronavirus, immunology, genetics & genomics, cell & molecular biology, HIV
Those We Lost in 2020
Amanda Heidt | Dec 18, 2020 | 7 min read
The scientific community bid farewell to researchers who furthered the fields of molecular biology, virology, sleep science, and immunology, among others.
an immune cell in blood
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens | Oct 14, 2022 | 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
The Scientist Staff | Mar 28, 2024
Top 7 in cell biology
Bob Grant | Feb 14, 2011 | 3 min read
A snapshot of the most highly ranked articles in cell biology and related areas, from Faculty of 1000
Luminescence Developments Help Scientists See The Light
James Kling | May 11, 1997 | 9 min read
Biologists are constantly seeking more sensitive assays to detect the presence of organisms or telltale DNA, RNA, and proteins. Although radioactive tags incorporated into the target itself (or into a complementary strand)-and later detected by Geiger counters or film exposures-have traditionally given good sensitivity, the problems of waste disposal and laboratory monitoring have driven a search for alternative tags that have radioactivity's sensitivity but avoid its hazards. Fluorescent tags-
Notable
Jeffrey Perkel | Jan 6, 2002 | 4 min read
J.A. Camarero et al., "Peptide chemical ligation inside living cells: In vivo generation of a circular protein domain," Bioorganic and Medicinal Chemistry, 9[9]:2479-84, September 2001. F1000 Rating: Recommended "To investigate whether chemo-selective peptide ligations work in vivo, the authors demonstrate the in vivo head-to-tail cyclization of a bioactive SH3 domain using native chemical ligation. The protein precursor was constructed using a clever combination of an intein-fusion protein an

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