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tag translocation developmental biology evolution

Close up photo of a wing
Unearthing the Evolutionary Origins of Insect Wings
Jef Akst | Apr 4, 2022 | 6 min read
A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
High-Tech Choir Master
Karen Hopkin | Jan 1, 2012 | 8 min read
Elaine Mardis can make DNA sequencers sing, generating genome data that shed light on evolution and disease.
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Keeping Time with Drosophila
Laura Bonetta | Feb 3, 2002 | 10 min read
Circadian clocks—the biological timekeepers that operate on a daily cycle—keep virtually every living creature in tune with its environment. These internal clocks regulate a wide range of fundamental biological processes, including movement, smell, sleep, mating, and feeding. A true circadian clock is endogenous; that is, it keeps time even in the absence of external cues. The clock can, however, be reset, or entrained, by daylight, allowing the synchronization of circadian rhythms t
Inner Sanctum
Jeanne Mcadara | May 28, 2000 | 9 min read
Reagents for Nuclear Hormone Receptor Research Courtesy of Karo Bio ABEffect of an agonist (red spheres) or agonist/antagonist (green spheres) on the C terminal helix of the ligand binding domain of the estrogen receptor The survival of a living system depends on its ability to communicate with and respond to its surroundings. Even the simplest unicellular organism has surface molecules for assessing the external environment. Evolution of complex life forms required intricate methods for respo
Creative Emulsification
Sabrina Richards | Nov 1, 2012 | 8 min read
Enhancing data collection from emulsion PCR reactions: three case studies
How Cells Find Their Way
Laura Defrancesco | Sep 2, 2001 | 5 min read
Organisms need to sense their environment. By sensing, they can develop, heal wounds, protect against invaders, and create blood vessels. Chemotaxis, or directional sensing, allows cells to detect chemicals with exquisite sensitivity. Some chemotactic cells can sense chemical gradients that differ by only a few percent from a cell's front to its back. Although discovery of the molecule types involved in chemotaxis, as with other kinds of cell signaling events, has mounted, the details of how thi

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