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tag glucose metabolism evolution immunology

Illustration of pink and blue DNA molecules.
Historic Adaptations May Now Make Us Susceptible to Disease
Dan Robitzski | Sep 16, 2022 | 5 min read
Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.
In the Long Run
Mary Beth Aberlin | Dec 1, 2012 | 3 min read
Can emulating our early human ancestors make us healthier?
Running on Empty
Bob Grant | Jun 1, 2017 | 10+ min read
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
What Sensory Receptors Do Outside of Sense Organs
Sandeep Ravindran | Sep 1, 2016 | 10+ min read
Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.
cards for a memory game, with pictures of pathogens turned over
Thanks for the Memories
Ruth Williams | Feb 1, 2015 | 10+ min read
B and T cells may be the memory masters of the immune system, but research reveals that other cells can be primed by pathogens, too.
Notable
Jeffrey Perkel | Apr 1, 2002 | 4 min read
A. Fahmy, G. Wagner, "TreeDock: A tool for protein docking based on minimizing van der Waals energies," Journal of the American Chemical Society, 124:1241-50, Feb. 20, 2002. "Current understanding of protein-protein and protein-ligand interactions is very limited. This paper describes a new algorithm that allows exploration of the interaction surface very fast and consequently at very fine resolution. The rationale behind the program is to keep the two molecules always in contact. This program
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
Notebook
The Scientist Staff | Mar 1, 1999 | 8 min read
David Holtzman and Friend SNAKE LOGIC David Holtzman, an assistant professor of brain and cognitive science at the University of Rochester, has loved snakes since childhood. But in college, when he wanted to investigate how snake brains develop, he found that serpents weren't exactly model organisms. "I wanted to devise a task that could show that snakes can learn as well as rodents--if you ask them to do the right thing," he recalls. Now Holtzman and his colleagues are doing just that (D.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo

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