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tag glucose metabolism evolution developmental biology

High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018 | 7 min read
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
New Technologies Shed Light on Caveolae
Ben Nichols | Jun 1, 2018 | 10+ min read
The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.
Ghosts in the Genome
Oliver J. Rando | Dec 1, 2015 | 10+ min read
How one generation’s experience can affect the next
What Sensory Receptors Do Outside of Sense Organs
Sandeep Ravindran | Sep 1, 2016 | 10+ min read
Odor, taste, and light receptors are present in many different parts of the body, and they have surprisingly diverse functions.
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
How to Create a Successful Fish Tale?
A. J. S. Rayl | Aug 19, 2001 | 10+ min read
More than 80 percent of the planet's living organisms exist only in aquatic ecosystems. Some may harbor secrets to human origins, and clues, treatments--perhaps even cures--for human disease. Some are critical bioindicators that portend the health of the biosphere. Yet, overall, scientists know little about the biochemical processes of these life forms. The vast, rich knowledge within the oceans and freshwater systems on Earth remains virtually untapped, because in the world of biological resear
Longevity
Jill Adams(juadams@the-scientist.com) | May 8, 2005 | 7 min read
During autophagy-literally "self-eating"-cells deliver cytoplasmic constituents, including whole organelles, to the lysosome for degradation.
Going Micro: Imaging Devices to Benefit Both Mouse and Biologist
Eugene Russo | Oct 25, 1998 | 8 min read
Mice everywhere are breathing a collective sigh of relief. Soon, far fewer small laboratory animals will be routinely sacrificed to allow researchers to observe the after-effects of gene mutations or other experimental manipulations. Instead, investigators will be able to track the implications of those changes in living specimens in exquisite detail and for extended periods of time, thus painting a fuller, more accurate picture of what's going on and why. At least, that's the likely scenario i

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