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At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

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image: Fat’s Influence on Cancer

Fat’s Influence on Cancer

By | April 3, 2017

Researchers at the annual American Association for Cancer Research meeting discuss the roles of adipose tissue and inflammation in the growth and spread of tumors.

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image: Book Excerpt from <em>The Politics of Cancer</em>

Book Excerpt from The Politics of Cancer

By | April 1, 2017

In Chapter 2, “Identifying the Culprits,” author Wendy Whitman Cobb describes how small-government, anti-regulation conservatism can hinder the fight against cancer.

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Hitting It Out of the Park

Hitting It Out of the Park

By | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Location, Location, Location

Location, Location, Location

By | April 1, 2017

Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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image: Infographic: Circadian Clock Affects Health and Disease

Infographic: Circadian Clock Affects Health and Disease

By | April 1, 2017

The body's rhythms could affect numerous ailments as well as how people respond to treatments.

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