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tag generics genetics genomics

Recent Trials for Fragile X Syndrome Offer Hope
Randi Hagerman | Sep 1, 2019 | 10+ min read
Despite a solid understanding of the biological basis of fragile X syndrome, researchers have struggled to develop effective treatments.
Prospecting for Gold in Genome Gulch
Amy Adams | Apr 14, 2002 | 9 min read
The human genome is much like the American West of the 1850s: Everyone wants a piece of the pie. Similar to gold prospectors of 150 years ago, biotech and pharmaceutical companies, and even universities, are frantically searching for the nuggets of gold that will help them find the mother lode—a gene whose function is sufficiently marketable to make all of the preliminary research worthwhile. Companies that do strike gold get to introduce new classes of drugs to the market. Others hope to
A Sharper Image
Bob Sinclair | Apr 29, 2001 | 10+ min read
Medical miracles abound, yet cancer continues to be a complex and challenging problem. "Cancer" is actually a generic, catchall term for the malignant tumors that are found in well over a hundred different diseases, but the basic concept is simple enough--a gene goes wrong and a tumor grows. Unfortunately, the reality is more complicated, involving an intricate sequence of phenomena and interactions in just a handful of the body's tens-of-trillions of cells. And therein lies the problem for rese
Variations on a Gene
Amy Francis | Jul 23, 2000 | 10+ min read
Photodisc Although President Bill Clinton surely had something in mind during his 2000 State of the Union address when he asked the nation to "celebrate our diversity," insights into human diversity at the molecular level are promising to speed drug discovery and revolutionize medicine to mark- edly improve human health. Individuals differ at one in 1,000 base pairs, which adds up to a whopping number of human genetic variations when applied to the roughly three billion base pairs of the human g
Genotyping with PCR
M. Tevfik Dorak | Jun 1, 2007 | 5 min read
How to choose the right approach
Lab Tools: Close Encounters
Jeffrey M. Perkel | Oct 1, 2008 | 7 min read
Protein-protein interaction assays for all occasions.
Cookbook For Eukaryotic Protein Expression: Yeast, Insect, and Plant Expression Systems
Christopher Smith | Nov 8, 1998 | 10+ min read
Date: November 9, 1998Baculovirus Expression Vectors In the recent past, efforts to elucidate the relationship between protein structure and biological function have intensified. Of particular interest is an understanding of the elements of sequence and structure that mediate specific functions. Often the protein of interest is in low abundance in its natural source and can be difficult to purify and/or unstable--subject to proteolytic cleavage or unfolding/non specific refolding during exhaust
The Scientist Top Innovations of 2008
Alison McCook | Dec 1, 2008 | 10+ min read
The Scientist Top Innovations of 2008 For the first time, we laud the ten most outstanding new products to hit the life science market. The life sciences move fast. Across the globe, companies are constantly churning out new products that they say will make your research smarter. For six years, we've ranked the vendors of life science equipment in our Life Science Industry Awards. Now, to recognize winning combinations of invention, vision and
Bridging the Gap with Bioelectronics
Deborah Fitzgerald | Mar 17, 2002 | 9 min read
Science has entered a new era in which molecules are being used as building blocks, moving parts, and even as electronic components. Biomolecules offer great potential as component parts because nature has already done much of the work; their very shapes and chemical makeup encode a variety of exploitable functions, including binding, catalysis, pumping, and self-assembly.2 A case in point: Science magazine hailed the first molecular-scale circuits as 2001's "Breakthrough of the Year."1 Researc
A Paradigm Shift in Stem Cell Research?
Ricki Lewis | Mar 5, 2000 | 9 min read
Photo: E.D. Laywell, UT MemphisMultipotent clones of cells derived from the adult human brain With the promises and challenges of stem cell research in the headlines, visions of artificial livers dance in the public's eye. Bioethicists, politicians, and citizens alike continue to debate whether public funds should be used to obtain cells from human embryos and fetuses. On the scientific front, however, the implications of stem cell research are even more profound than offering replacement parts.

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