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image: Think Before You Fire

Think Before You Fire

By | May 1, 2015

Industry layoffs may save a few dollars, at the cost of losing the collective brainpower of thousands of scientists.

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image: Book Excerpt from <em>p53</em>

Book Excerpt from p53

By | April 1, 2015

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.

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image: Bursting Cancer’s Bubble

Bursting Cancer’s Bubble

By | April 1, 2015

Scientists make oxygen-filled microbubbles designed to increase tumor sensitivity to radiation.

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image: Capsule Reviews

Capsule Reviews

By | April 1, 2015

Junk DNA, Cuckoo, Sapiens, and Cool

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: Mining the Outliers

Mining the Outliers

By | April 1, 2015

Even when a clinical trial fails, some patients improve. What can researchers learn from these exceptional responders?

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image: Setbacks and Great Leaps

Setbacks and Great Leaps

By | April 1, 2015

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

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image: Signaling Resistance

Signaling Resistance

By | April 1, 2015

Activating signaling pathways, rather than individual genes, reveals roles for both growth and dedifferentiation in establishing resistance to cancer treatments.

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image: The Challenges of Precision

The Challenges of Precision

By | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

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image: Tracking Miracles

Tracking Miracles

By | April 1, 2015

A panel of oncologists discusses cases of exceptional responders, or cancer patients whose tumors disappear after a brief period of chemotherapy.

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