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tag protein protein interactions genetics genomics disease medicine

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Punctual Proteins Aid Parasites
Laura Tran, PhD | Feb 1, 2024 | 3 min read
A protein’s timely appearance is crucial for Toxoplasma gondii’s unique replication cycle.
Unraveling Protein-Protein Interactions
Leslie Pray | Jan 26, 2003 | 8 min read
Courtesy of Adrian Arakaki THERE'S GOLD IN THEM THERE COMPLEXES: Digging up protein-protein interactions with MULTIPROSPECTOR. Using a computer instead of a pipette, Jeffrey Skolnick contemplates the subtle forces that bring proteins together. His first computational forays helped decipher the quaternary structure of proteins--the interactions between subunits in molecules such as tropomyosin. Now Skolnick, executive director of the Buffalo Center of Excellence in Bioinformatics, Buffalo
A Comprehensive Guide to Proteomics
An Introductory Guide to Proteomics
Sejal Davla, PhD | Jan 16, 2023 | 5 min read
Deconstructing concepts, approaches, and data analysis in proteomics workflows.  
Illustration of HIV virus
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD | Dec 12, 2022 | 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 
Probing Protein Interactions
Laura Defrancesco | Apr 14, 2002 | 8 min read
The challenge of proteomics is personified in the Greek god, Proteus. The keeper of all knowledge, past, present and future, Proteus would not give up any information easily; even while held down, he would struggle and assume different forms before giving anything up. Remarkably, proteomics, and proteins for that matter, were not named after Proteus, but the imagery could not be more fitting. It's still anyone's guess what the final gene count will be in the human genome, let alone the total nu
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
FDA Approves Gene Therapy for Spinal Muscular Atrophy
Ashley Yeager | May 27, 2019 | 3 min read
At $2 million for a single dose, Novartis’s Zolgensma is the most expensive medicine to date, but still less expensive over a lifetime than another approved drug for the rare genetic disease.

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