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tag double helix genetics genomics

Researchers can obtain epigenetic information in addition to genetic insights from a single DNA sample.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | Mar 12, 2024 | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
Celebrating 60 Years of the Double Helix
Dan Cossins | Apr 25, 2013 | 2 min read
Genome Biology speaks to a scientist involved in the discovery of the structure of DNA, and asks modern geneticists to highlight the key advances that have followed.
Genotoxic Effects of Base and Prime Editing
Kamal Nahas, PhD | Jan 12, 2024 | 5 min read
A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 
Week in Review: April 22–26
Jef Akst | Apr 26, 2013 | 2 min read
Double helix celebrates 60; detecting calories without taste; bacteria vs. tumor; perceptual consciousness in babies
3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.
CRISPR Gene Editing: Cas9 and Beyond
Johanna Pruller, PhD and Deanna MacNeil, PhD | Nov 29, 2023 | 7 min read
Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms.
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | Oct 10, 2022 | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Top 7 in Genomics & Genetics
Bob Grant | Jul 19, 2011 | 3 min read
A snapshot of the most highly ranked articles in genomics, genetics, and related areas, from Faculty of 1000
CRISPR Can Tag RNA
Kerry Grens | Mar 21, 2016 | 1 min read
Modifications to the DNA-slicing program allow for monitoring the movement of messenger RNA.
Decoding DNA: New Twists and Turns
Kerry Grens | Jun 1, 2013 | 10+ min read
Highlights from a series of three webinars on the future of genome research, held by The Scientist to celebrate 60 years of the DNA double helix

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