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tag dissection evolution disease medicine

Microscope image of A549-ACE2 lung cells coinfected with SARS-CoV-2 and a reporter vector containing a key regulatory variant of interest in the region on human chromosome 3
How Genes from Neanderthals Predispose People to Severe COVID-19
Alakananda Dasgupta | Feb 22, 2023 | 4 min read
Researchers dissect the Neanderthal-derived region on chromosome 3 that drives severe COVID-19 to zero in on the key causal variants.
A person lying on a bed checks the reading on a digital thermometer. A table with a bowl of oranges and various medications is in the background.
How Mild Is Omicron Really?
Dan Robitzski | Jan 14, 2022 | 9 min read
Early reports that Omicron causes less-severe disease than Delta seem to be borne out, but it’s not yet clear to what extent that’s due to the variant itself versus the populations it’s infecting.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
3d render Blood cells (depth of field)
William Harvey Revolutionized Our Understanding of Circulation
Dhun Sethna | Sep 12, 2022 | 4 min read
A puzzle for millennia, the movement of blood through the body was solved by an English physician in the 17th century, paving the way for modern medical technologies.
Chronobiology Researchers Say Their Field's Time Has Come
Ricki Lewis | Dec 10, 1995 | 5 min read
Like many life sciences, chronobiology is a field that has transitioned from the organismal level, to anatomical dissection, to molecular analysis. 
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Week in Review: June 16–20
Tracy Vence | Jun 20, 2014 | 2 min read
Early Neanderthal evolution; developing antivirals to combat polio; the mouth and skin microbiomes; insect-inspired, flight-stabilizing sensors
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Do Pathogens Gain Virulence as Hosts Become More Resistant?
Andrew F. Read and Peter J. Kerr | Oct 1, 2017 | 10+ min read
Emerging infections provide clues about how pathogens might evolve when farm animals are protected from infection.

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