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tag fecal transplant evolution disease medicine

Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Are Phages Overlooked Mediators of Health and Disease?
Catherine Offord | Feb 1, 2021 | 10+ min read
Bacteria-infecting viruses affect the composition and behavior of microbes in the mammalian gut—and perhaps influence human biology.
Collage of those featured in the article
Remembering Those We Lost in 2021
Lisa Winter | Dec 23, 2021 | 5 min read
As the year draws to a close, we look back on researchers we bid farewell to, and the contributions they made to their respective fields.
illustration of colorful microbes inside a person's stomach and intestines
How Commensal Gut Bacteria Keep Pathogens in Check
Alejandra Manjarrez, PhD | Oct 14, 2021 | 7 min read
Recent studies describe how resident microbiota appear to outcompete unwelcome visitors, either with superior weaponry or by guzzling up local resources.  
antibiotics antibiotics resistance persister bacteria bacteriophage
Opinion: We Need More than New Antibiotics to Fight Resistance
Neil S. Greenspan and Arturo Casadevall | Nov 1, 2019 | 3 min read
Metabolic disrupters, phages, and other approaches are going to be needed to treat the broadest possible range of patients infected by bacterial pathogens resistant to multiple drugs.
black lab mice microbiome
Microbes May Take Some of the Blame for the Reproducibility Crisis
Emma Yasinski | Apr 5, 2019 | 4 min read
Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.
microbiome drugs
How the Microbiome Influences Drug Action
Shawna Williams | Jul 15, 2019 | 10+ min read
Through their effects on metabolism and immunity, bacteria in the gut affect whether medications will be effective for a given patient.
Wrestling with Recurrent Infections
Gayatri Vedantam and Glenn S. Tillotson | May 1, 2011 | 9 min read
By Gayatri Vedantam and Glenn S. Tillotson Wrestling with Recurrent Infections Clostridium difficile is evolving more robust toxicity, repeatedly attacking its victims, and driving the search for alternative therapies to fight the infection. photoillustration by Sean Mccabe; Science Photo Library (boy); Sebastian Kaulitzki/ Istockphoto.com (Intestines); Olena Timashova/Istockphoto.com (Green bacteria); Jiri Flogel/Istockphoto.com (Blue bacteria) As infectiou
Sharing the Bounty
Michelle G. Rooks and Wendy S. Garrett | Aug 1, 2011 | 10+ min read
Gut bacteria may be the missing piece that explains the connection between diet and cancer risk.

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