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tag computer programming evolution

Targeted Comparative Sequencing Illuminates Vertebrate Evolution
Ricki Lewis | Dec 8, 2002 | 6 min read
Image: Courtesy of Elliott Marguiles  PIPS ON PARADE: Researchers used a MultiPipMaker to show the alignments, expressed as percent identity plots, between a human reference sequence and several other species. This is a 20 kb region surrounding exon 2 of the MET gene. Gap-free alignable segments are represented as horizontal lines along the human reference sequence; the line's height represents the identity of that alignment. Aristotle envisioned humanity as the pinnacle of a "Great Chai
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
An Offensive Playbook
Mary Beth Aberlin | Feb 1, 2014 | 3 min read
Developing nonaddictive drugs to combat pain
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Checking the Alignment
Jane Salodof Macneil | Sep 21, 2003 | 9 min read
Courtesy of European Bioinformatics Institute  KNOWLEDGE GAPS? Sequence alignments offer clues to both the function and evolution of novel genes. But a bewildering array of algorithms and parameters leaves many researchers unable to use these programs to their fullest potential. In the beginning, there was Needleman-Wunsch, which begat Smith-Waterman, which begat FASTA, which begat BLAST, and so on. Peel away the information technology jargon surrounding these alignment algorithms, and a
Combinatorial Libraries: Life's Tinker Toys
Gail Dutton | May 18, 2003 | 9 min read
Courtesy of UC Davis Medical Center  COMBI-KING: Kit Lam brings his expertise in combinatorial chemistry, an innovative technique for creating millions of new chemical compounds in just days, to the UC Davis Cancer Center. It's the new mix and match. In the computer industry, programmers refer to modularity--the ability to shuffle different sections of computer code to create new software. In the life sciences, the modules are peptides or molecular fragments that can be combined to yield
2018 Top 10 Innovations
The Scientist | Dec 1, 2018 | 10+ min read
Biology happens on many levels, from ecosystems to electron transport chains. These tools may help spur discoveries at all of life's scales.
Making DNA Data Storage a Reality
Catherine Offord | Oct 1, 2017 | 10+ min read
A few kilograms of DNA could theoretically store all of humanity’s data, but there are practical challenges to overcome.
Bibliographic Software Adding New Features, Becoming Web Savvy
Robert Finn | Jul 7, 1996 | 10+ min read
Web Savvy Hard times for science are turning out to be good times for publishers of personal bibliographic software. As scientists feel increasing pressure to apply for grants from several agencies and submit articles to multiple journals, the value of bibliographic software rises. These programs, which store detailed reference information and export them in a wide variety of formats, are ubiquitous in scientific offices and laboratories (F. Hoke, The Scientist, Jan. 11, 1993, page 18; June 27,
Seeing sharks from space
Stephen Pincock | Nov 6, 2005 | 3 min read
There's always been an air of mystery around whale sharks.

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