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tag supercomputer genetics genomics

Sequencing Stakes: Celera Genomics Carves Its Niche
Ricki Lewis | Jul 18, 1999 | 8 min read
J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard
$1,000 Genome at Last?
Tracy Vence | Jan 15, 2014 | 2 min read
Illumina says its newest sequencing system can churn out whole human genomes for $1,000 apiece.
A Flood in Genomics
Brendan Maher | Nov 25, 2001 | 9 min read
Nine months have passed since draft sequences of the human genome were first published.1,2 One human gestation period later, the genome, as deciphered by the International Human Genome Sequencing Consortium, still screams toward its projected Spring 2003 finish date. "The trajectory we're on for meeting that goal is precisely on target," assures Francis Collins, director, National Human Genome Research Institute (NHGRI) and spokesperson for the largest public biological science project in histor
Bioinformatics, Genomics, and Proteomics
Christopher Smith | Nov 26, 2000 | 10+ min read
Data Mining Software for Genomics, Proteomics and Expression Data (Part 1) Data Mining Software for Genomics, Proteomics and Expression Data (Part 2) High-throughput (HT) sequencing, microarray screening and protein expression profiling technologies drive discovery efforts in today's genomics and proteomics laboratories. These tools allow researchers to generate massive amounts of data, at a rate orders of magnitude greater than scientists ever anticipated. Initiatives to sequence entire genom
Diagnosing Cancer: A Genomics and Proteomics Approach
Tom Hollon | Sep 21, 2003 | 7 min read
In 1996, Jeff Trent and colleagues published the first paper describing DNA microarrays as tools for pinpointing gene variants underlying various tumor properties.1 Now, as president and scientific director of Translational Genomics Research Institute (TGEN), in Phoenix, Trent is using microarrays to look for gene expression patterns that can be applied to developing diagnostics. The role of microarrays, Trent says, "will be on the discovery side. Testing all 30,000 genes against a diagnosti
Biotechnology Reenergized
Aristides Patrinos(ari.patrinos@science.doe.gov) | Mar 13, 2005 | 6 min read
The completion of the Human Genome Project (HGP) symbolizes the entry of biology into the "big science" arena.
On the Fast Track in Functional Proteomics
A. J. S. Rayl | Apr 1, 2001 | 8 min read
Graphic: Leza Berardone Researchers in Canada and Denmark are employing mass spectrometry, three-dimensional tissue biology, and supercomputing to blaze a trail in functional proteomics research. In the process, they're putting their company, MDS Proteomics Inc., on the fast track in the latest race to develop new drug targets and eventually better treatments for all kinds of diseases. By using this combination of technologies, MDS Proteomics is accelerating the process of identifying, analyzin
DNA Software Takes The Drudgery Out Of Molecular Biology
Ricki Lewis | Sep 15, 1991 | 8 min read
Author: RICKI LEWIS, p.23 It is expected to take some 15 years to determine the sequence of the 3 billion base pairs that make up the human genome--roughly 550,000 base pairs per day. An analytical task of this magnitude would have been unthinkable just a few years ago, but today's rapidly advancing computer technology has made the international effort to sequence the human genome possible. C.B.S. Scientific Co. Inc. P.O. Box 856 Del Mar, Calif. 92014 Phone: (619) 755-4959 Fax: (619) 755-
The Alpha Project
Steve Bunk | Feb 23, 2003 | 7 min read
One day, genomic data will be translated into language that can be used to find new diagnostic and therapeutic targets for disease. Computers will mine DNA codes to build nanomachines, and "smart fabrics" will contain sensing capabilities modeled on living things. So says Shankar Shastry, chairman of electrical engineering and computer sciences at the University of California at Berkeley. "Bio is my bet on where the new set of glamour technologies will be," he predicts. But even the small step
Ten Technologies in Five Years
Sam Jaffe(sjaffe@the-scientist.com) | Dec 5, 2004 | 8 min read
When scientists make long-term research plans, they must try to anticipate how emerging technologies will influence their work in the coming years.

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