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tag subglacial lake cell molecular biology

Confocal Microscopy: Viewing Cells As """"Wild Animals""""
Franklin Hoke | Jan 24, 1993 | 6 min read
Bio-Rad Microscience Division 19 Blackstone St.Cambridge, Mass. 02139 (800) 444-1422 Fax: (617) 864-9328 Leica Inc. 111 Deer Lake Rd. Deerfield, Ill. 60015 (800) 248-0123 Fax: (708) 405-0147 Meridian Instruments Inc. 2310 Science Pkwy. Okemos, Mich. 48864 (800) 247-8084 Fax: (517) 349-5967 Molecular Probes Inc. 4849 Pitchford Ave. Eugene, Ore. 97402 (503) 465-8300 Fax: (503) 344-6504 Molecular Dynamics Inc. 880 E. Arques Ave. Sunnyvale, Calif. 94086 (800) 333-5703 Fax: (408) 773-8343 Ni
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Distinguishing Th1 and Th2 Cells
Jeffrey Perkel | May 13, 2001 | 10+ min read
Reagents That Distinguish Th1 and Th2 cells Courtesy of R&D SystemsSchematic representation of cytokines influencing the development of antigen-activated naive CD4+ T cells into Th1 and Th2 cells. Editor's note: Although individual techniques are associated with specific researchers in this article, it should be noted that these investigators commonly use several different techniques to analyze T lymphocyte populations. The human body is constantly under siege. It must defend itself fr
Escaping the Heat
Deborah Fitzgerald | Nov 12, 2000 | 10+ min read
Nonradioactive Kinase Assay Kits Safety concerns and economic considerations have fueled a growing trend in the biomedical sciences: to shun the use of radioactivity when practical. Nonradioactive options for numerous applications have become widely available, including a number of nonradioactive kinase assay kits. Assays from different manufacturers employ a wide range of strategies. Most of these kits utilize antibodies, but two nonimmunochemical approaches use fluorescently tagged substrates
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019 | 6 min read
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Software Solutions to Proteomics Problems
Bob Sinclair | Oct 14, 2001 | 10 min read
As genome sequencing becomes a regular occurrence, biology's attention can turn to the next logical step: proteomics. Fundamentally, proteomics is nothing less than the complete catalog of every protein in a given tissue, organ, or organism under a defined growth or disease state. Sometimes this definition is expanded to include protein-protein interactions. The data describe the types and quantities of proteins present and also indicate other proteins with which these molecules are complexed.
Death Watch II: Caspases and Apoptosis
Jorge Cortese | Jun 24, 2001 | 10 min read
Caspase Related Reagents Courtesy of Bingren Hu, Queen's Medical Center, Hawaii. Provided by Cell Signaling TechnologyConfocal micrograph of double immunostaining for cleaved caspase-3 (green) and propidium iodide (red) in newborn rat brain tissue. This section shows control and transient cerebral ischemia. Editor's Note: This is the second article in our two-part series on cell death. The first part: J. Cortese, "Death watch I: Cytotoxicity detection," The Scientist, 15[5]:26, March 5, 2001.
Applications Of Image Analysis Systems Expand Beyond The Research Lab
Ricki Lewis | Oct 27, 1996 | 10+ min read
TIME EFFICIENT: The AMBIS radioisotopic imager from Scanalytics/CSPI. Already an invaluable tool in some basic research, image analysis is edging into the classroom and the clinic. "Any field of life science that can put a video camera onto a microscope will begin to use image analysis," predicts Richard Cardullo, an associate professor of biology at the University of California, Riverside. In general, the technique acquires, digitizes, and then processes a microscope or scanned image, enhan
Automation Advances in Proteomics
Aileen Constans | Aug 24, 2003 | 10 min read
Courtesy of the Institute for Systems Biology  MOVING FORWARD: The LCQ Deca XP, an electrospray ionization/ion trap mass spectrometer from Thermo Finnigan The sheer number of new protein-focused mass spectrometry (MS) instruments introduced last year is a testament to the growing importance of the technique in proteomics research. Coupled to this trend is a growing need for automation of upfront sample preparation to feed these analytical machines. From the specialized academic lab to hi
Digital Upgrade
Amber Dance | May 1, 2010 | 7 min read
table thead tr td { border-bottom: 2px solid #000000; }table tr td { font-size: 12px; font-family:"Trebuchet MS", Arial, Helvetica, sans-serif; border-bottom: 2px solid #949494; }#featureArticleContent ul li { font-size: 14px; font-family: "Trebuchet MS", Arial, Helvetica, sans-serif; } By Amber Dance Digital Upgrade How to choose your lab’s next electronic lab notebook The bound, graph-lined laboratory not

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