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image: One Receptor, Two Ligands, Different Responses

One Receptor, Two Ligands, Different Responses

By | August 31, 2016

Host and bacterial ligands that interact with the same cell-surface receptor induce different activities in human macrophages. 

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image: One Antigen Receptor Induces Two T cell Types

One Antigen Receptor Induces Two T cell Types

By | August 26, 2016

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

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Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

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image: Wanted: Transcriptional Regulators

Wanted: Transcriptional Regulators

By | August 1, 2016

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

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A 3-D carbon nanotube mesh enables rat spinal tissue sections to reconnect in culture.

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Mismatched ancestral origins of mitochondrial and nuclear DNA boost mouse health.

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image: Immune Cell–Stem Cell Cooperation

Immune Cell–Stem Cell Cooperation

By , , and | July 1, 2016

Understanding interactions between the immune system and stem cells could pave the way for successful stem cell–based regenerative therapies.

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image: Immune Cells' Roles in Tissue Maintenance and Repair

Immune Cells' Roles in Tissue Maintenance and Repair

By , , and | July 1, 2016

The cells of the mammalian immune system do more than just fight off pathogens; they are also important players in stem cell function and are thus crucial for maintaining homeostasis and recovering from injury.

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image: Single-Cell RNA Sequencing Reveals Neuronal Diversity

Single-Cell RNA Sequencing Reveals Neuronal Diversity

By | June 23, 2016

Using a new approach to analyze the transcriptomes of thousands of individual cell nuclei in postmortem brains, researchers identify multiple neuronal subtypes.

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image: Exercise-Induced Muscle Factor Promotes Memory

Exercise-Induced Muscle Factor Promotes Memory

By | June 23, 2016

Running releases an enzyme that is associated with memory function in mice and humans.  

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