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tag gene drive evolution neuroscience developmental biology

Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
A three-dimensional rendered image of neuron cell network on black background.
Assembloids Unlock the Roles of Key Neurodevelopment Disease Genes
Aparna Nathan, PhD | Sep 27, 2023 | 3 min read
Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
First Successful Gene Drive in Mammals
Abby Olena, PhD | Jan 23, 2019 | 4 min read
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
Using Brain Organoids in Human Health and Disease Research
Using Brain Organoids in Human Health and Disease Research
The Scientist | Jan 17, 2024 | 1 min read
Learn how scientists across life science and engineering disciplines join forces to build brain organoids that mimic neurodevelopment.
Top 7 in Developmental Biology
Edyta Zielinska | Jul 12, 2011 | 3 min read
A snapshot of the most highly ranked articles in developmental biology and related areas, from Faculty of 1000.
Tentacles test tenets of evolution
Elie Dolgin | Nov 17, 2008 | 3 min read
Novel genes, rather than regulatory DNA, underlie the evolution of morphological traits, according to research published today (Nov. 17) in __PLoS Biology__. The new linkurl:study;http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0060278 reports that genes found in simple freshwater animals -- but not in any other evolutionary lineage -- can drive changes in body plan, and stokes the flames of a long-standing debate among evolutionary developmental biologist
PCR tubes placed into the 96-well loading chamber of a PCR thermocycler instrument.
Directing Superior Reagents for Better PCR Results
The Scientist and MilliporeSigma | Oct 2, 2023 | 3 min read
Directed evolution approaches are creating new reagents to help a tried-and-true technique reach new heights.

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