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tag human proteome project neuroscience

Advances in the functional characterization of newly discovered microproteins hint at their diverse roles  in health and disease
The Dark Matter of the Human Proteome
Annie Rathore | Apr 1, 2019 | 10 min read
Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.
Improved purification for proteomics
Jonathan Weitzman(jonathanweitzman@hotmail.com) | Dec 15, 2002 | 1 min read
Combining TAP tagging and RNAi techniques improves eukaryote protein complex purification.
This image depicts the fruit fly nerve cord connectome. It highlights 930 neurons, a subset of the full set of reconstructed neurons.
The Expansion of Volume Electron Microscopy
Danielle Gerhard, PhD | Sep 8, 2023 | 6 min read
A series of technological advancements for automation and parallel imaging made volume electron microscopy more user friendly while increasing throughput.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Blue glowing neuron projections
Silent Synapses May Provide Plasticity in Adulthood
Holly Barker, PhD | Dec 13, 2022 | 4 min read
Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.
The Proteome in Pictures
Helen Dell | Mar 13, 2005 | 3 min read
In the largest project of its kind, Swedish scientists are studying normal and cancerous tissues to discover not only the location and abundance of all human proteins, but also how these are affected by disease states.
Time for a human interactome project?
Marc Vidal | Mar 1, 2006 | 6 min read
FEATUREHuman Interactome Project An investment of $100 million should be enough to correlate the genome with function, and identify new basic research and drug targets BY MARC VIDALĀ© THOM GRAVESMapQuest and global positioning systems have radically changed the way we travel. By showing us where we are relative to where we want to go, these tools simplify the job of getting from point A to point B, and make trave
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Scorpion tags tumors
Amy Coombs | Oct 1, 2007 | 3 min read
Fluorescence indicates chlorotoxin binding to medulloblastoma cells in a mouse (right). Credit: Image by Mandana Veiseh, courtesy of AACR" />Fluorescence indicates chlorotoxin binding to medulloblastoma cells in a mouse (right). Credit: Image by Mandana Veiseh, courtesy of AACR Within minutes after being stung by the scorpion known as the deathstalker (Leiurus quinquestriatus), weakness starts to kick in. The feeling quickly spreads, paralyzing its prey (typically insects) for hours -
Pushing Proteomics
Jim Kling | Apr 14, 2002 | 4 min read
Genomics is slowly but surely moving off center stage, replaced by proteomics. Though proteomics is a young field that hasn't fully found its stride, two new developments provide glimpses of the future. At the end of February, attendees of the Cambridge Healthtech Institute (CHI) Genome Tri-Conference 2002 in Santa Clara, Calif., got their first glimpse of the Protein Atlas of the Human Genome™. Developed by Abingdon, UK-based Confirmant Ltd.—a joint venture of Abingdon, UK-based Ox

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