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tag human proteome project ecology immunology

Week in Review: May 26–30
Tracy Vence | May 30, 2014 | 4 min read
Human proteome cataloged; island-separated crickets evolved silence; molecule shows promise for combatting coronaviruses; study replication etiquette; another call for STAP retraction
Pufferfish Genomes Probe Human Genes
Ricki Lewis | Mar 17, 2002 | 7 min read
It may be humbling to think that humans have much in common with pufferfish, but at the genome level, the two are practically kissing cousins. "In terms of gene complement, we are at least 90% similar—probably higher. There are big differences in gene expression levels and alternate transcripts, but if you're talking about diversity, number and types of proteins, then it's pretty difficult to tell us apart," says Greg Elgar, group leader of the Fugu genome project at the Medical Research C
One Step Beyond: Going Beyond Genomics With Proteomics And Two-Dimensional Gel Technology
Laura Defrancesco | Jan 3, 1999 | 10+ min read
Proteomes and 2D Gel Apparatus Providers Big science has moved on to proteins. With the new brand of science termed proteomics--named by the Australians Marc Wilkins and Keith Williams to mean the "set of PROTEins encoded by the genOME"--the push is on around the globe to produce a complete description of a cell/tissue/organism in terms of the proteins produced. The challenge is all the greater because the expressed protein pattern changes with time and environment--responding to developmenta
Probing Protein Interactions
Laura Defrancesco | Apr 14, 2002 | 8 min read
The challenge of proteomics is personified in the Greek god, Proteus. The keeper of all knowledge, past, present and future, Proteus would not give up any information easily; even while held down, he would struggle and assume different forms before giving anything up. Remarkably, proteomics, and proteins for that matter, were not named after Proteus, but the imagery could not be more fitting. It's still anyone's guess what the final gene count will be in the human genome, let alone the total nu
Planning the Future of Plant Genomics
Eugene Russo | Jul 21, 2002 | 5 min read
Image: Courtesy of National Sciences Foundation Arabidopsis Plant genomics researchers stand at a crossroads. Behind them are the completed genome sequences of rice1 and the model mustard plant Arabidopsis thaliana.2 Now, armed with insights gained from both plant and animal sequencing projects, plant biologists must decide how to proceed with future sequencing, proteomics, and functional genomics endeavors--and how to allot precious basic research dollars while, at the same time, keeping
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
BIOTEC
BIOTEC | Jan 12, 2010 | 5 min read
color = "#DF1F26";.pullquote_left1, .pullquote_right1, .pullquote_left, .pullquote_right { color: #FEF8F6; background: #939598 }.breakhead { color: #DF1F26; border-bottom: 1px solid #DF1F26; } BIOTEC Excellence in Science, Relevance to National Agenda Established in 1983, BIOTEC is one of four centers under the umbrella of the National Science and Technology Development Agency (NSTDA), an autonomous government body. The Center serves as a
Get the Basics
Gail Dutton | Nov 10, 2002 | 6 min read
Photo: Courtesy of Michelle Lizott Waniewski  DROP AND GIVE ME 20! Attendees at the 2002 NEB workshops labor through basic training. If you've ever been confused by the jargon of molecular biology, you are not alone. With biotechnology in the news day by day, it is easy to forget that for many of us--even for some readers of The Scientist--the tools, techniques, and concepts that undergird much of this research are foreign. To help keep up, some scientists are queuing up to learn the bas
Biochemical, Reagents Kits Offer Scientists Good Return On Investment
Holly Ahern | Jul 23, 1995 | 8 min read
Investment Author:Holly Ahern If you were to ask several life scientists to name a particular biochemical product that they simply could not do without, you'd probably get a myriad of answers that would mirror the research interests of the group you questioned. A molecular evolutionist trying to differentiate two closely related species of monkeys by restriction fragment-length polymorphism (RFLP) analysis might cite restriction enzymes, which can cut DNA into pieces of varying length. A cell b

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