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tag chop evolution

Inspired by Nature
Daniel Cossins | Aug 1, 2015 | 10+ min read
Researchers are borrowing designs from the natural world to advance biomedicine.
Mapping Subtelomeres
Ricki Lewis | Oct 14, 2001 | 4 min read
In genetics, certain terms sometimes mask what scientists do not yet understand, such as "junk DNA." Similarly, the chromosomal regions just proximal to the tips--the subtelomeres--have been dubbed "buffers," ill-defined DNA sequences that somehow support the telomeres, which control the cell cycle and cellular aging. A team of researchers from the Wistar Institute in Philadelphia, the University of California, Irvine, and John Radcliffe Hospital in Oxford, UK, has used single-copy sequences in
Human Genes: How Many?
Tom Hollon | Oct 14, 2001 | 6 min read
Counting human genes ought to be straightforward. Tracking telltale signs--motifs for promoters, translation start sites, splice sites, CpG islands--gene counters must by now be mopping up, finalizing chromosomal locations of every human gene already known, and predicting whereabouts of all the rest. Insert one human genome sequence, turn the bioinformatics crank, and genes gush out like a slot machine jackpot, right? "No, no, no," says Bo Yuan, of Ohio State University, having a laugh over th

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