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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Contributors

Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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image: Control ALT, Delete Cancer

Control ALT, Delete Cancer

By , , and | April 1, 2015

Treating cancer by shutting down the alternative lengthening of telomeres (ALT) pathway

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image: In Custody

In Custody

By | April 1, 2015

Expert tips for isolating and culturing cancer stem cells

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image: Manipulative Microbiomes

Manipulative Microbiomes

By | April 1, 2015

Gut bacteria control tumor growth via the mammalian immune system.

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image: Professional Marksman

Professional Marksman

By | April 1, 2015

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

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image: The CAR T-Cell Race

The CAR T-Cell Race

By | April 1, 2015

Tumor-targeting T-cell therapies are generating remarkable remissions in hard-to-beat cancers—and attracting millions of dollars of investment along the way.

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image: The Challenges of Precision

The Challenges of Precision

By | April 1, 2015

Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.

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image: To Each His Own

To Each His Own

By | April 1, 2015

Cancer treatment becomes more and more personal.

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image: My Mighty Mouse

My Mighty Mouse

By | April 1, 2015

Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.

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