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tag tumor necrosis factor disease medicine

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Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
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Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021 | 3 min read
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
TRAILing autoimmune disease
Tudor Toma(t.toma@ic.ac.uk) | Feb 9, 2003 | 1 min read
TRAIL deficiency leads to the induction of autoimmune diseases.
Frontlines
Hal Cohen | Feb 17, 2002 | 5 min read
New evidence points to brain trauma as an environmental risk factor for Alzheimer disease (AD). 
probiotic infographic
Infographic: Gut Microbes Change How Well Drugs Work
Shawna Williams | Jul 15, 2019 | 2 min read
Our resident bacteria can affect the activity of immunotherapies and other medicines in the body.
Molecular Biology
The Scientist Staff | Mar 29, 1992 | 1 min read
S.A. Rosenberg, P. Aebersold, K. Cornetta, A. Kasid, et al., "Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction," New England Journal of Medicine, 323:570-78, 1990. Steven A. Rosenberg (National Cancer Institute, Bethesda, Md.): "The practice of medicine in the future may well be transformed as we learn to treat disease not by surgery, radiation, or drugs, but rather by genetic alteration
Cytokine protection in multiple sclerosis
Tudor Toma(t.toma@ic.ac.uk) | Jun 6, 2002 | 1 min read
Ciliary neurotrophic factor and leukaemia inhibitory factor have protective effects in a model of multiple sclerosis.
News feature
Vector image of black body with head surrounded by white clouds
Multiple Possible Causes of Long COVID Come into Focus
Natalia Mesa, PhD | Sep 28, 2022 | 10+ min read
Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  
Bespoke Stem Cells for Brain Disease
Nsikan Akpan | Jan 14, 2013 | 3 min read
Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.

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