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image: Rare T Cells Fight Cancer

Rare T Cells Fight Cancer

By | May 1, 2017

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.

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From fish harvests to cottonwood forests, organisms display evidence that species change can occur on timescales that can influence ecological processes.

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Guppies transplanted between different communities in Trinidadian streams evolved in response to changes in predation threat in just a few generations.

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By analyzing the genomes of 161 dog breeds, scientists discover how and when certain canine breeds emerged.

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The state’s board of education approves new standards that ease up on having students dig into scientific issues relevant to “intelligent design” arguments.

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image: New Giant Virus Group Reported

New Giant Virus Group Reported

By | April 6, 2017

A genomic analysis of “Klosneuviruses” suggests that they evolved from small viruses that accumulated genetic material over time, but not all virologists are convinced. 

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image: Contributors

Contributors

By | April 1, 2017

Meet some of the people featured in the April 2017 issue of The Scientist.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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Measuring PD-L1 levels was a great start. Now we need to quantify more protein biomarkers, assess the tumor mutational landscape, and examine immune cell signatures, too.

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