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» Y chromosome and immunology

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image: A Movable Defense

A Movable Defense

By | January 1, 2015

In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.

4 Comments

image: Why, Oh Y?

Why, Oh Y?

By | January 1, 2015

A toothpick and a bit of chance shaped David Page’s career, which he has dedicated to understanding the mammalian Y chromosome and fetal germ cell development.

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image: Stress Fractures

Stress Fractures

By | January 1, 2015

Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.

6 Comments

image: The Year in Pathogens

The Year in Pathogens

By | December 29, 2014

Ebola, MERS, and enterovirus D68; polio eradication efforts; new regulations on potentially dangerous research

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image: Focus on Sex

Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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image: Repurposed Retroviruses

Repurposed Retroviruses

By | December 18, 2014

B cells have commandeered ancient viral sequences in the genome to transmit antigen signals.

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image: Vanishing Y Chromosomes

Vanishing Y Chromosomes

By | December 4, 2014

A new study reveals an association between smoking and rates of Y chromosome loss in blood cells, which may explain elevated cancer risk among male smokers.

1 Comment

image: Platelets Fan Inflammation

Platelets Fan Inflammation

By | December 4, 2014

The circulating blood cells bind to neutrophils, prompting inflammation-related activity in these immune cell partners.

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image: Gut Microbes Trigger Malaria-Fighting Antibodies

Gut Microbes Trigger Malaria-Fighting Antibodies

By | December 4, 2014

A carbohydrate antigen found on cells of E. coli and other species prompts a potent immune response against malaria-causing parasites in mice.

1 Comment

image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.

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