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image: CRISPR–Enabled Epigenome Editing

CRISPR–Enabled Epigenome Editing

By | April 6, 2015

Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.

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image: Enzyme Improves CRISPR

Enzyme Improves CRISPR

By | April 1, 2015

A smaller Cas9 protein enables in vivo genome engineering via viral vectors.

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image: Contributors

Contributors

By | April 1, 2015

Meet some of the people featured in the April 2015 issue of The Scientist.

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image: From Many, One

From Many, One

By | April 1, 2015

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?

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image: Short, Strong Signals

Short, Strong Signals

By | March 25, 2015

Methylation increases both the activity and instability of the signaling protein Notch.

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image: Quantity or Quality?

Quantity or Quality?

By | March 1, 2015

Living longer doesn’t necessarily mean living healthier.

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image: Tricky Transfections

Tricky Transfections

By | March 1, 2015

A combination of microinjection and electroporation inserts genes into hard-to-reach cells.

2 Comments

image: Fertility Treatment Fallout

Fertility Treatment Fallout

By | January 1, 2015

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

8 Comments

image: Grab ’n’ Glow

Grab ’n’ Glow

By | January 1, 2015

Engineered proteins can tether multiple fluorescent molecules to give a brighter signal—and that’s not all.

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image: Contaminants Could’ve Accounted for STAP

Contaminants Could’ve Accounted for STAP

By | December 29, 2014

Embryonic stem cells likely mucked up the cultures used in the debunked “stimulus-triggered acquisition of pluripotency” studies.

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