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A test tube-based genome-labeling technique has been brought under the microscope.

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image: Top Technical Advances 2016

Top Technical Advances 2016

By | December 15, 2016

The year’s most impressive achievements include methods to watch translation in cells, trace cell fates, avoid mitochondrial mutations, edit DNA, and build antibiotics from scratch.

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image: Synthetic Sensors

Synthetic Sensors

By | December 1, 2016

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

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image: Infographic: How to Build a Synthetic Sensor

Infographic: How to Build a Synthetic Sensor

By | December 1, 2016

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

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image: Neural Connectome Method Uses mRNA Barcodes

Neural Connectome Method Uses mRNA Barcodes

By | November 1, 2016

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.  

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image: Genetic Tags Illuminate Where Neurons Extend

Genetic Tags Illuminate Where Neurons Extend

By | November 1, 2016

Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.

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image: How to Track Translation in Living Cells

How to Track Translation in Living Cells

By | October 1, 2016

Four independent research groups develop techniques for visualizing peptide production in living cells.

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image: Science History: The First Transgenic <em>Arabidopsis</em>

Science History: The First Transgenic Arabidopsis

By | October 1, 2016

Tweaks to a transformation protocol in 1986 cemented the little plant's mighty role in plant genetics research.

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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Group Proposes Strategies to Improve Antibodies

Group Proposes Strategies to Improve Antibodies

By | September 5, 2016

An expert committee encourages reagent providers to adopt one of five methods to validate products.

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