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tag brain imaging developmental biology cell molecular biology

Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
L.B. Zimmerman, J.M. De Jesús-Escobar, R.M. Harland, "The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4," Cell, 86:599-606, 1996. (Cited in more than 180 papers since publication) Comments by Richard M. Harland, Choh Hao Li professor of biochemistry and molecular biology, University of California, Berkeley Richard M. Harland Researchers had long suspected that the protein noggin's interaction with bone morphogenetic proteins (BMPs) dictated devel
Developmental Biology
The Scientist Staff | Jan 3, 1999 | 3 min read
S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 papers since publication) Comments by Eddy M. De Robertis, Investigator, Department of Biological Chemistry, Howard Hughes Medical Institute, University of California, Los Angeles Eddy M. De Robertis In 1924, two scientists identified a small group of embryonic cells that tell their neighbor
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Developmental Biology
The Scientist Staff | Apr 1, 1996 | 3 min read
Edited by Karen Young Kreeger H. Roelink, A. Augsburger, J. Heemskerk, V. Korzh, S. Norlin, A. Ruiz i Altaba, Y. Tanabe, M. Placzek, T. Edlund, T.M. Jessell, J. Dodd, "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord," Cell, 76:761-75, 1994. (Cited in nearly 90 publications as of February 1996) Comments by Henk Roelink, University of Washington SIGNALS FROM SONIC HEDGEHOG: Using cDNA, University of Washington's Henk Roelink and col
Developmental Biology
The Scientist Staff | Feb 1, 1999 | 6 min read
Edited by: Paul Smaglik P. Carmeliet, V. Ferreira, G. Breier, S. Pollefeyt, L. Kieckens, M. Gertsenstein, M. Fahrig, A. Vandenhoeck, K. Harpal, C. Eberhardt, C. Declercq, J. Pawling, L. Moons, D. Collen, W. Risau, A. Nagy, "Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele," Nature, 380:435-9, 1996. (Cited in more than 235 papers since publication) Comments by Andras Nagy, senior staff scientist, Mount Sinai Hospital, Samuel Lunenfeld Research Institute, To
Developmental Biology
The Scientist Staff | Jun 11, 1995 | 2 min read
Edited by Neeraja Sankaran Seeding Plaques:Peter Lansbury and colleagues identified a possible mechanism for the formation of amyloid plaques in Alzheimer's disease. J.T. Jarrett, E.P. Berger, P.T. Lansbury, Jr., "The carboxy terminus of the b amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease," Biochemistry, 32:4693-7, 1993. (Cited in 53 publications through April 1995) Comments by Peter Lansbury, Jr., Massachusetts Instit
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Molecular Biology
The Scientist Staff | Jan 20, 1991 | 3 min read
C.K. Glass, S.M. Lipkin, O.V. Devary, M.G. Rosenfeld, "Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer," Cell, 59, 697-708, 17 November 1989. Christopher K. Glass (School of Medicine, University of California, San Diego, La Jolla): "Retinoic acid receptors appear to exert profound effects on vertebrate development by binding to target genes and altering the rates at which they are transcribed in response to retinoic acid. Because t

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