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image: Week in Review: April 10–14

Week in Review: April 10–14

By | April 14, 2017

CRISPR patent ruling appealed; CRISPR-based nucleic acid test; an experimental gene therapy for Duchenne muscular dystrophy and a cell-based protocol for Parkinson’s disease show promise in mice

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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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Scientists identify a mutation in the CRY1 gene in people with abnormal sleeping patterns.

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image: Week in Review: April 3–7

Week in Review: April 3–7

By | April 7, 2017

Virus triggers gluten intolerance in mice; UK bank offers clinic-ready hESC lines; researchers debate giant virus origins; cephalopods edit RNA; scientists screen noncoding genome with CRISPR

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23andMe customers can now receive information about genetic risk for diseases including Parkinson’s and celiac.

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

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image: Mutations Linked to Secondary Cancers

Mutations Linked to Secondary Cancers

By | April 4, 2017

Childhood cancer survivors with mutations in certain cancer-risk genes have a higher risk of developing additional neoplasms later in life, according to research presented at the American Association for Cancer Research annual meeting.

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At the annual American Association for Cancer Research meeting, researchers discuss the importance of understanding the epigenetic contributors to cancer progression and treatment response.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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