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tag mitochondrial disease evolution immunology

Top 7 in immunology
Edyta Zielinska | Mar 7, 2011 | 3 min read
A snapshot of the most highly ranked articles in immunology and related areas, from Faculty of 1000
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
A blood sample containing white and red blood cells.
Enhancing Cell Morphology-Based Analysis
The Scientist and Deepcell | Aug 3, 2023 | 3 min read
Learn how the latest AI-driven technology uses morphology to comprehensively analyze and sort cell populations.
2020 end of year roundup science news wildfire pandemic coronavirus covid-19 salivary glands tubarial mitochondria in blood neanderthal dna in african genome first blood test for alzheimer's inclusivity black in x stem
The Biggest Science News of 2020
Kerry Grens | Dec 23, 2020 | 6 min read
Neanderthal DNA surprises in modern humans, the first blood test for Alzheimer’s, a discovery of new human salivary glands, and, oh yeah, a pandemic
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
No Mo’ Slow Flow
Jeffrey M. Perkel | Jan 1, 2012 | 7 min read
Tools and tricks for high-throughput flow cytometry
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Notable
Jeffrey Perkel | Jan 20, 2002 | 3 min read
T. Sicheritz-Pontén, S.G. Andersson, "A phylogenomic approach to microbial evolution," Nucleic Acids Research, 29[2]:545-52, Jan. 15, 2001. F1000 Rating: Must Read "The paper describes methods and computer programs for automated phylogenetic analysis of complete genome datasets, as well as useful visualization tools for the results. The tools should be useful to those looking for genes that may have unusual evolutionary histories relative to other genes in the same genome." —Jonath
Mitochondria at the Crossroads of Life and Death
Amy Adams | Oct 10, 2004 | 8 min read
Professors P. Motta & T. Naguro/Photo ResearchersEach of our cells hangs in a delicate balance between life and death. Which path the cell takes depends on a dense web of signaling pathways that all converge on a single cellular switch, the mitochondrion. Most of the time, pro-life signals keep the mitochondrial membrane intact and encourage the organelle to churn out ATP. But when signals from the outside or accumulated toxins within the cell tip the scales, mitochondria push the cell down
Death in the Balance
Laura Defrancesco | Jun 24, 2001 | 5 min read
In 1997, to the surprise of many researchers, mitochondria reclaimed the limelight of apoptosis research when several groups observed that cytochrome c released from the mitochondria could induce apoptosis in cell-free systems.1,2 A hot research topic decades ago, mitochondria excitement cooled in the 1970s when researchers agreed on the mechanisms of oxidative phosphorylation (ox-phos). Now, mitochondria-mediated apoptosis is believed to be central to a number of major debilitating diseases, in

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