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tag anti epileptic drugs neuroscience

3D image of a neuron cell network with a red glow representing inflammation.
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | Jun 1, 2023 | 2 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
A pregnant woman gets her blood pressure checked by a doctor
U.K. Health Authority Investigates Epilepsy Drug’s Link to Autism
Peter Hess, Spectrum | Aug 30, 2022 | 3 min read
The Medicines and Healthcare products Regulatory Agency’s investigation comes after a study showed prenatal exposure to topiramate roughly triples a child’s likelihood of having autism or intellectual disability.
Fly’s Blood-Brain Barrier Has Circadian Rhythms
Abby Olena, PhD | Mar 8, 2018 | 3 min read
In Drosophila, the tissue is more permeable to drugs at night, offering a possible explanation for why some medicines work better at certain times of day.
RNAs
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Amber Dance | Jun 1, 2019 | 8 min read
New ways to search for druggable RNAs and matching small molecules
Probing the Role of Tau Protein in Disease
Jef Akst | Nov 16, 2016 | 2 min read
Researchers at the Society for Neuroscience conference discuss tau’s contributions to epilepsy, Alzheimer’s disease, and other tauopathies.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Diana Kwon | Oct 1, 2019 | 5 min read
A growing body of evidence supports the theory that neural hyperactivity and hyperconnectivity precede the pathological changes that lead to neurodegeneration.
Brain Activity Breaks DNA
Sabrina Richards | Mar 24, 2013 | 3 min read
Researchers find that temporary double-stranded DNA breaks commonly result from normal neuron activation—but expression of an Alzheimer’s-linked protein increases the damage.
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
Clinical Trial Reversals Forcing Biotech Firms To Refine Strategy
Susan Dickinson | Sep 18, 1994 | 7 min read
Under pressure to reap return on investment, companies are seeking ways to ensure success in designing drug tests This past July, Synergen Inc. suspended clinical trials of its anti-inflammatory drug candidate, Antril--being tested to fight sepsis--for lack of efficacy. Faced with the setback to its $100 million-plus investment, the Boulder, Colo.-based biotech was forced to lay off more than half its work force and shut down two

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