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tag national cancer institute evolution developmental biology culture

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Book Excerpt from When Brains Dream
Robert Stickgold and Antonio Zadra | Dec 1, 2020 | 8 min read
Ferreting out the biological function of dreaming is a frontier in neuroscience.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Maximize In Vitro Culture Possibilities
Linda Raab | Oct 25, 1998 | 4 min read
From Redmond, et al., "Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model," In Vitro Cellular & Developmental Biology--Animal, Volume 31:601-609. Copyright 1995 by the Society for In Vitro Biology. Reproduced with permission of the copyright owner. The Cellmax™ culture system uses hollow fiber bioreactor technology in applications as diverse as secreted protein production, lymphocyte expansion, and cellular co-cultivation. The concept of
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Cancer Institute Turns To Cell Line Screening
David Ansley | Apr 29, 1990 | 6 min read
Looking for compounds to kill tumors, Michael Boyd abandons leukemic mice and tries a radically new, unprecedentedly large assay In a sharp break from its past, the National Cancer Institute has abandoned a 30-year-old system for finding compounds that kill tumors and has replaced it with an elaborate but unproven factory-style operation. In the new program, unique in its scope, 20,000 compounds and extracts will be tested against a broad array of human tumor cells each year. The compounds wi
How to Calculate Mutation Rate for Evolutionary Biology
Amber Dance | Jul 1, 2018 | 6 min read
Four ways to study mutation rate, a crucial statistic in studies of evolution
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

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