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Immune Cells and ALS: A Balance Between Life and Death
Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.
Immune Cells and ALS: A Balance Between Life and Death
Immune Cells and ALS: A Balance Between Life and Death

Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.

Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.

Alzheimer's Disease, immunology

Microglia stained black
Opinion: Harnessing Microglia Cells to Stave Off Neurodegeneration
Kristine Zengeler, The Conversation | Dec 8, 2022 | 5 min read
Dialing up the activity of a protein called SYK in the brain’s “janitors” could provide an avenue to treat Alzheimer’s and other neurodegenerative diseases.
Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Holly Barker, PhD | Aug 5, 2022 | 4 min read
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
Accurately measure a neurodegeneration biomarker from blood samples
Detecting an Accessible Biomarker of Neurodegeneration
ProteinSimple, a Bio-Techne brand | Nov 4, 2021 | 1 min read
A sensitive, automated immunoassay measures neurofilament light from patient blood samples.
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena, PhD | Jan 20, 2021 | 3 min read
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
2020 end of year roundup science news wildfire pandemic coronavirus covid-19 salivary glands tubarial mitochondria in blood neanderthal dna in african genome first blood test for alzheimer's inclusivity black in x stem
The Biggest Science News of 2020
Kerry Grens | Dec 23, 2020 | 6 min read
Neanderthal DNA surprises in modern humans, the first blood test for Alzheimer’s, a discovery of new human salivary glands, and, oh yeah, a pandemic
Breaking Down Barriers
The Scientist | Oct 19, 2020 | 1 min read
Looking at the future of neurodegeneration research!
Gum Disease Could Drive Alzheimer’s: Study
Ashley Yeager | Jan 24, 2019 | 2 min read
An enzyme of the bacteria Porphyromonas gingivalis has been found in the brains of patients with the disorder, and causes neurodegeneration in mice.
Researchers Develop Potential Blood Test for Alzheimer’s Disease
Catherine Offord | Feb 1, 2018 | 2 min read
The test uses levels of plasma amyloid-β to estimate the buildup of protein plaques in the brain.
Switching the Bait
Edyta Zielinska | Feb 1, 2012 | 2 min read
Turning a standard technique into an unbiased screen for diagnostic biomarkers
What Causes Alzheimer’s?
W. Sue T. Griffin | Sep 1, 2011 | 10 min read
Researchers and pharma companies have tried to attack this disease by reducing amyloid plaques, but inflammation may be the real culprit.
The Cytokine Cycle
W. Sue T. Griffin | Sep 1, 2011 | 1 min read
The initiating cause of Alzheimer’s disease is still unknown. However, from our studies it’s clear that many types of neuronal damage—­­from traumatic brain injury, to epilepsy, infection, or genetic predisposition—­can activate brain immune cells—microglia and astrocytes-- promoting them to produce IL-1 and S100 inflammatory cytokines.
Blood’s Role in the Aging Brain
Edyta Zielinska | Aug 31, 2011 | 3 min read
A blood protein involved in allergy contributes to the decline in brain function and memory in aging mice.
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