The Scientist

» Alzheimer's Disease and immunology

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image: Tangle Trigger

Tangle Trigger

By | January 1, 2015

An enzyme that cleaves tau protein in acidic cellular conditions may trigger early events in Alzheimer’s disease.

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image: Stress Fractures

Stress Fractures

By | January 1, 2015

Social adversity shapes humans’ immune systems—and probably their susceptibility to disease—by altering the expression of large groups of genes.

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image: The Year in Pathogens

The Year in Pathogens

By | December 29, 2014

Ebola, MERS, and enterovirus D68; polio eradication efforts; new regulations on potentially dangerous research

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Focus on Sex

By | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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image: Repurposed Retroviruses

Repurposed Retroviruses

By | December 18, 2014

B cells have commandeered ancient viral sequences in the genome to transmit antigen signals.

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image: Shoring Up Golgi To Slow Alzheimer’s

Shoring Up Golgi To Slow Alzheimer’s

By | December 8, 2014

Blocking activity of a kinase in a mouse model protects Golgi in cells and reduces the build-up of amyloid β, a primary component of Alzheimer’s disease.

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image: Platelets Fan Inflammation

Platelets Fan Inflammation

By | December 4, 2014

The circulating blood cells bind to neutrophils, prompting inflammation-related activity in these immune cell partners.

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image: Gut Microbes Trigger Malaria-Fighting Antibodies

Gut Microbes Trigger Malaria-Fighting Antibodies

By | December 4, 2014

A carbohydrate antigen found on cells of E. coli and other species prompts a potent immune response against malaria-causing parasites in mice.

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image: All Systems Go

All Systems Go

By | December 1, 2014

Alan Aderem earned his PhD while under house arrest for protesting apartheid in South Africa. His early political involvement has guided his scientific focus, encouraging fellow systems biologists to study immunology and infectious diseases.

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image: Bespoke Cell Jackets

Bespoke Cell Jackets

By | December 1, 2014

Scientists make hydrogel coats for individual cells that can be tailored to specific research questions.

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