The Scientist

» Alzheimer's Disease and disease/medicine

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image: The Regenerator

The Regenerator

By | December 1, 2015

In his search for effective therapies for Parkinson’s disease, Lorenz Studer is uncovering pluripotency switches and clues to what makes cells age.


image: BRCA1 Linked to Alzheimer’s

BRCA1 Linked to Alzheimer’s

By | November 30, 2015

The cancer-related protein BRCA1 is important for learning and memory in mice and is depleted in the brains of Alzheimer’s patients, according to a study.


image: Cortical Census

Cortical Census

By | November 26, 2015

Scientists document the characteristics and connections of mouse neocortical neurons to establish the most detailed microcircuit map to date.

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image: Fatal-Disease Drug in Limbo

Fatal-Disease Drug in Limbo

By | November 25, 2015

A panel of experts advised the US Food and Drug Administration that BioMarin Pharmaceutical has not demonstrated efficacy of its new drug for Duchenne muscular dystrophy.


image: How Gastric Bypass Can Kill Sugar Cravings

How Gastric Bypass Can Kill Sugar Cravings

By | November 19, 2015

A type of bariatric surgery eliminates gut-to-brain signals that trigger sugar highs, a mouse study shows.  

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image: Blood-Gut Barrier

Blood-Gut Barrier

By | November 12, 2015

Scientists identify a barrier in mice between the intestine and its blood supply, and suggest how Salmonella sneaks through it.


image: Breaching the Blood-Brain Barrier

Breaching the Blood-Brain Barrier

By | November 11, 2015

Researchers deliver cancer-fighting drugs to a patient’s brain via the bloodstream, penetrating the blood-brain barrier for the first time.


image: Life Scientists Honored

Life Scientists Honored

By | November 9, 2015

Breakthrough Prizes of $3 million each go to five researchers in the life sciences, recognizing their pioneering work in optogenetics, disease-associated mutation analyses, and ancient DNA sequencing.

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Some antibodies designed to eliminate the plaques prominent in Alzheimer’s disease can aggravate neuronal hyperactivity in mice.

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image: Week in Review: November 2–6

Week in Review: November 2–6

By | November 6, 2015

How Ebola hides from immune cells; gut microbes’ role in immunotherapy response; new mechanisms of hearing loss; butterflies use milkweed toxins to ward off predators


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