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tag down syndrome genetics genomics disease medicine
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD
| Mar 7, 2024
| 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening.
Immunity Genes May Play a Role in Down Syndrome
Kamal Nahas, PhD
| Jul 6, 2023
| 4 min read
Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.
Identical Twins Carry Distinctive Epigenetic Marks: Study
Chloe Tenn
| Sep 30, 2021
| 2 min read
Researchers found more than 800 sites in the genome where the twins bore the same chemical tags.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD
| Feb 16, 2024
| 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
Precision Medicine: A New Era in Cancer Therapy
Rebecca Roberts, PhD
| Dec 15, 2023
| 6 min read
Precision medicine helps clinicians tailor individual treatments, addressing genetic mutations, tumor microenvironment variations, and therapeutic resistance.
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens
| Oct 14, 2022
| 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD
| Nov 11, 2022
| 3 min read
A study finds that
XIST
, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD
| Mar 20, 2024
| 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
Redesigning Medicine Using Synthetic Biology
Alison Halliday, PhD,
Technology Networks
| Jun 21, 2023
| 5 min read
Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.
Doctors Treat a Rare Genetic Condition Before Patient Is Born
Dan Robitzski
| Nov 10, 2022
| 2 min read
Thanks to continued weekly medications, a 16-month-old girl shows no symptoms of a severe genetic disease that typically kills children before they turn two.
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