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tag organ transplant culture

An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
With CRISPR, Modeling Disease in Mini Organs
Tanya Lewis | May 6, 2016 | 3 min read
Organoids grown from genetically edited stem cells are giving scientists a new tool to screen drugs and test treatments.
Cellular therapy. 3d illustration
Expert JeWell-ry Designers
Natalia Mesa, PhD | Oct 17, 2022 | 3 min read
Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.
Capsule Reviews
Annie Gottlieb | Mar 1, 2013 | 3 min read
The Undead, Frankenstein's Cat, The Universe Within, and Physics in Mind
How to Track Cell Lineages As They Develop
Kelly Rae Chi | Dec 1, 2016 | 7 min read
Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.
My Mighty Mouse
Megan Scudellari | Apr 1, 2015 | 10+ min read
Personal drug regimens based on xenograft mice harboring a single patient’s tumor still need to prove their true utility in medicine.
Trials of the Heart
Christopher Thomas Scott(cscott@the-scientist.com) | Jul 3, 2005 | 5 min read
Adult human stem cells may offer the opportunity to use one of biomedical science's most promising technologies without the ethical dilemmas of embryonic cells.
'Heart in a Box': Global Effort Works to Put the Pieces Together
Paul Smaglik | Mar 14, 1999 | 5 min read
Graphic: Marlene J. Viola Some say it takes a village to raise a child. Michael V. Sefton proposes that it will take a world to build a heart. Sefton, a University of Toronto chemical engineering professor, leads an international effort called the Living Implants from Engineering (L.I.F.E.) Initiative, whose goal is to create a bioengineered heart in 10 years. To meet that mark, participants must grapple with a host of scientific concerns and more mundane matters. Research questions that must b
Building a Better Mouse
Edyta Zielinska | Apr 1, 2010 | 10+ min read
A notoriously poor proxy for the human experience of cancer, mouse models are now undergoing a major renovation.
Porcine Possibilities
Ricki Lewis | Oct 15, 2000 | 8 min read
Courtesy of PPL TherapeuticsA new generation of pigs. Headlines in late summer 2000 introduced long-awaited reports on pig cloning and retroviral transmission to mice, pig cells healing rat spinal cords, and a gaff by Dolly dad Ian Wilmut erroneously heralding halt of xenograft work at the Roslin Institute near Edinburgh, Scotland. So it seemed that the question of whether pigs can pass their retroviruses to humans might finally be on the road to resolution. Not quite. Pigs, as the purveyors o

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